Hydrocephaly, Schizencephaly, Spondylocostal Dysplasia, and Hypoparathyroidism in an Infant of a Diabetic Mother

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Infant of a Diabetic Mother with Spondylocostal Dysostosis and Multiple Congenital Anomalies

Jarcho-Levin syndrome is a rare genetic disorder characterized by respiratory insufficiency and multiple spine and rib abnormalities. It was first described by Jarcho and Levin in 1938. Spondylocostal dysostosis (SCD) and spondylothoracic dysostosis (STD) are the subtypes of Jarcho-Levin Syndrome, which show a hereditary picture. Autosomal dominant, autosomal recessive, and sporadic cases have ...

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Coexistence of schizencephaly and intracranial arteriovenous malformation in an infant.

A 9-month-old infant had unilateral closed-lip schizencephaly in the right parietal lobe, which coexisted with an arteriovenous malformation in the nearby temporal area. Cranial MR showed a right parietal cleft lined with gray matter between the right lateral ventricle and the subarachnoid space, and cluster hypointensities throughout the right temporal lobe. Cerebral angiography revealed a rig...

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Spondylocostal dysplasia (Jarcho-Levin syndrome) comprises multiple malformations of the vertebrae and ribs coupled with a characteristic clinical picture of short neck, scoliosis, short trunk, and deformity of the rib cage. We describe a patient with the syndrome who also had spina bifida and diastematomyelia. We surmise that this association is not coincidental. Additional evidence is needed ...

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ژورنال

عنوان ژورنال: Acta Endocrinologica (Bucharest)

سال: 2017

ISSN: 1841-0987,1843-066X

DOI: 10.4183/aeb.2017.494